https://bugs.winehq.org/show_bug.cgi?id=53021 --- Comment #13 from Florian Schreiner <florian.schreiner(a)protonmail.com> --- After some further testing it seems the "clean" install used mono 7.2.0 although the default for wine 6.0.3 would be mono 5.1.1 from what I could gather. Through testing all versions since mono 5.1.1 to 7.2.0 I found that ChemDraw only works with mono 7.0.0 or higher, since every earlier version crashes somewhere inside mono. ChemDraw doesn't even launch under these conditions. I don't know how relevant this is to this specific problem but still wanted to share my findings in case of any further complications. -- Do not reply to this email, post in Bugzilla using the above URL to reply. You are receiving this mail because: You are watching all bug changes.