How to find out locking problem

Happy New Year!

i notice, that since 1.3 i get quite offten locking issue. It looks
like, that last OK version was 1.2-rc7. This problem happens in
Bioshock on load/save, but i noticed that other users have same
problem with games on the same game engine.

Could someone help me, what should i do in this lockin-case as
first, please?

Thanks in advance! Regards
W.

...
fixme:thread:SetThreadIdealProcessor (0x734): stub

err:ntdll:RtlpWaitForCriticalSection section 0x7deac200
"x11drv_main.c: X11DRV_CritSection" wait timed out in thread 001a,
blocked by 0041, retrying (60 sec)

err:ntdll:RtlpWaitForCriticalSection section 0x5486584 "?" wait
timed out in thread 0045, blocked by 0044, retrying (60 sec)