I was looking into updating the AppDB with more recent results for PCB Artist* and discovered that on a fresh Wine install that the application opens and creates new files incredibly slowly (it now takes 23 minutes vs. old performance of ~5 seconds).  I ran a regression test and discovered that an added feature in OLE32 is responsible for this "regression."  I am, admittedly, not an expert on OLE32 - so I'm hoping that someone else has some thoughts on how to resolve this issue.
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226363f5dfb9caa8313e425c7f85ed9fe581f1fe is first bad commit
commit 226363f5dfb9caa8313e425c7f85ed9fe581f1fe
Author: Vincent Povirk <vincent@codeweavers.com>
Date:   Fri Dec 4 17:33:50 2009 -0600

    ole32: Implement transacted storage.

:040000 040000 79e7adf6177afe9cb8bfdea75270edb00026c5e5 abc173741982ee971ac490738917d735c6869a78 M    dlls
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Erich Hoover
ehoover@mines.edu

* Free proprietary application, direct download:
http://www.4pcb.com/downloads/pcbartist/PcbArtist_1_3_2.exe