Now,we don't run wine in Chrome OS.
Google also think they can run windows executable files.
My idea is about how to use wine in the OS.
Google Chrome has two types of extensions:one is the extension,that support only web technology.the other is PPAPI,Google Native Client.
Here's the overview↓
https://developers.google.com/native-client/dev/overview
For example,Flash Player uses PPAPI.
C/C++ programs can be transformed and run in its sandbox.
then we can run wine in Chrome OS.
I think if wine supports Chrome OS,Google helps us.