https://bugs.winehq.org/show_bug.cgi?id=51420
--- Comment #21 from mitchell4136@gmail.com --- I am able to reproduce this bug on 495.44-13 driver published in the official arch repos on November 26th on an RTX 2060 super card. I'm willing to bet this is a multi monitor issue.
There is another big teport that also mentions an external monitor and is almost certainly a duplicate of this bug:
https://bugs.winehq.org/show_bug.cgi?id=51891