http://bugs.winehq.org/show_bug.cgi?id=12560
--- Comment #100 from hash HASH.DuOrden@gmail.com 2009-04-05 16:38:16 --- (In reply to comment #99)
Can you confirm that any of these games use DXTC/S3TC textures?
I can try compile latest wine with S3TC disabled and see if these games are running but I do know that LotRO and EVE Online do use S3TC as they refused to run with out S3TC before.