https://bugs.winehq.org/show_bug.cgi?id=47148
--- Comment #7 from Gabriel Ivăncescu gabrielopcode@gmail.com --- Yes, if you can, please test the latest patch, the former one didn't handle hwnd == NULL properly (it was my mistake, sorry) and also is extra "safe" on full screen or apps anchored at (0,0) on the desktop (though that has more to do with working around vst-bridge).
If, however, it still doesn't work as in 4.6, please try to attach a +cursor trace (use 'export WINEDEBUG=+cursor' before launching the game in terminal, and redirect its output to a file), ideally with and without the patch for comparison purposes.