http://bugs.winehq.org/show_bug.cgi?id=34556
--- Comment #5 from Dave Kimble ppalloy@gmail.com 2013-09-20 01:43:38 CDT --- After "rm -rf ~/.wine" my launcher icons in lxpanel were still present, and when clicked there was a dialog saying ~/.wine was being reconfigured, and then nothing else happened. I suppose that's not surprising.
So I tried to install a safe application via teracopy-setup.exe right-> Open With > Wine Windows Program Loader > and it said the file was corrupt. npp.6.4.5.Installer.exe the same.
And Wine has disappeared from Ubuntu/lxpanel's top level menu.
I think it's time to do a clean install, don't you?