http://bugs.winehq.org/show_bug.cgi?id=23516
--- Comment #31 from 3vi1 winehq.org@eternaldusk.com 2010-12-24 18:48:32 CST --- I saw the same results as Brandon: Setting the number of files to 8192 does *not* help (Kubuntu Natty (11.04) - 2.6.37-11-generic #25-Ubuntu SMP)
In fact, in my case, the sound drops seem to be entirely due to timing/CPU issues.
If I run Folding@Home in the background for 12 threads on my i980x, I'll get the sound drops immediately when entering a map, and randomly every few minutes thereafter. If I kill the F@H process, the sound will suddenly start working for many maps before it will finally and randomly drop.