http://bugs.winehq.org/show_bug.cgi?id=30148
--- Comment #24 from julusp@gmail.com --- Thanks Ken for pointing them out.
Unfortunately I am not able to test it currently against SWTOR, however, I have tested it against Path Of Exile which suffers from same issue (well a lot of games does). There is still no improvement and from 40s sample, the 30s are spend in NTMapViewOfSection call (and from there 14s map_file_into_view > 14s __mmap and 13s map_view> 12s wine_anon_mmap > 12s __mmap)
Seems like it is still hitting some OSX specific barrier, which cannot be so simply avoided... Even copying whole game to ramdisk and running from there does not speed up anything (results are pretty much the same)