http://bugs.winehq.org/show_bug.cgi?id=16666
--- Comment #6 from Austin English austinenglish@gmail.com 2009-04-02 13:48:16 --- (In reply to comment #5)
In loader/main.c there's a pre_exec() function defined for FreeBSD. Maybe you need that on OpenBSD as well.
I'm sure it needs something, but it probably needs its own. OpenBSD is very different from FreeBSD.
Just running './wine' gives the error. I'm attempting to contact OpenBSD developers for more information, but knowing how that went last time, doubt it'll get much done...