https://bugs.winehq.org/show_bug.cgi?id=46142
--- Comment #8 from abienz@gmail.com --- So adding 'gameoverlayrenderer' to my Library overrides, and setting it to 'disabled' allowed me to launch and play my games with usual performance.
In my game prefixes I don't have xinput overrides, but in my standard wine prefix where Steam is installed I have the following:
xinput1_3 (native, builtin) xinput9_1_0 (native, builtin)
Not sure if this is relevant to the above issues mentioned in the comments too.