https://bugs.winehq.org/show_bug.cgi?id=51420
--- Comment #19 from Kurt Kartaltepe kkartaltepe@gmail.com ---
I can't reproduce this at all on 495.44 (and I've never seen it before on any driver version since I got the 3090 on launch day on 24 Sept. 2020), so I'm guessing this is probably limited to older drivers/cards now.
It is trivially replicable on 6.21 by running regedit.exe and trying to use it. I am using a GTX 1070. I wouldn't classify this as "older drivers/cards" as basically all newer models are unattainable by the average user. As my wallet and time is not unlimited I dont have other hardware to test personally.