http://bugs.winehq.org/show_bug.cgi?id=16757
--- Comment #55 from Austin English austinenglish@gmail.com 2009-01-08 09:49:01 --- (In reply to comment #53)
Any bahavior causing different bahavior than Windows is a bug. Please clarify what is supported configuration?
Note that many programs and games cannot be installed under Wine at all but if to run them from existing Windows installation, they work well.
It can work, yes, but it's hacky and there are plenty of cases where it doesn't work. There have been problems in the past with NTFS partitions, and while most have been fixed, last I checked, there were still a couple minor bugs there.
Installing under Wine helps to minimize possible causes of the bug, making it easier to fix.