https://bugs.winehq.org/show_bug.cgi?id=53910
--- Comment #16 from Rafał Mużyło galtgendo@o2.pl --- Well, it's a bit tricky, as 'xset dpms force off' no longer triggers this in 100% of the cases (and I've yet to figure out what differs when it does).
I'm seeing an odd behavior that might give an additional clue: in Unnamed Space Idle (f2p Godot engine game), once the bug hits, a vertical strip on the right side of the game window is cut off from mouse input; I can resize the game window and if I make it small enough (as the interface scales), the elements that were within that vertical strip become accessible, but if I stretch the window back, the strip is still insensitive; also something odd happens upon using 'Reset Window Size' option in the settings while in the buggy state: the window content that should fill the whole window gets letterboxed instead (two horizontal black strips in the window) (no, that interface reset doesn't fix the problem).
I'll write back once I've either figured out how to trigger this manually or that I need to wait until it triggers on its own.