http://bugs.winehq.org/show_bug.cgi?id=20024
--- Comment #14 from André H. nerv@dawncrow.de 2009-09-13 13:05:07 --- (In reply to comment #12)
To sum up - Linux desktop recognizes mouse movements and hovering over hover- sensitive regions/objects through Crossloop. But mouse clicks and key presses are not seen by or passed on from Wine. Only thing between Crossloop and the operating system is Wine. Therefore we suspect there is a bug in Wine.
You still haven't answered the question, does a windowsapp or maybe just winecfg running in the same wine instance recognize mouse clicks or key input?