https://bugs.winehq.org/show_bug.cgi?id=57645
--- Comment #12 from EasyNetDev devel@easynet.dev --- The that bug https://bugs.winehq.org/show_bug.cgi?id=48678 LokProgrammer was entering in an infinite loop and you had to kill the app. With newer versions of LokProgrammer and WineHQ is just not communicate at all even is sees the serial ports.