https://bugs.winehq.org/show_bug.cgi?id=50893
--- Comment #4 from jqt58958@zwoho.com --- I have found the solution to this strange behaviour: It was the same as https://bbs.archlinux.org/viewtopic.php?pid=1965664#p1965664
For some reason, my home directory had an atime of 2040 which caused a Y2038 overflow of the 32-bit timestamp integer. A simple touch /home/user1 to bring atime back to 2021 solved it.
There might still be a bug that needs fixing in wine although it can presumably wait till 2038 :). I leave it up to you whether to do something about it or close this bug as resolved.