http://bugs.winehq.org/show_bug.cgi?id=27522
--- Comment #14 from Pilot pilota51@gmail.com 2011-06-23 17:09:24 CDT --- Tried the Tomb Raider: Anniversary demo and can confirm it is very much like UT3, except menus are also affected (like BF1942), the range isn't limited while clicking. and the behavior between virtual desktop and full-screen is as described by Fab. Also tried it with both of my mice, same results as my other tests: It works fine with the Microsoft mouse.
I tried using both mice simultaneously and I can move one and click the other with no issue, it only happens when the Logitech is doing both the moving and clicking.