http://bugs.winehq.org/show_bug.cgi?id=29706
--- Comment #7 from Myk Taylor myk002@yahoo.com 2012-06-27 10:38:25 CDT --- hrm, this may not be the problem. wine's implementation of the dir command for the cmd executable uses GetDiskFreeSpaceExW to get the disk free status line, and that works just fine for my 4TB free. Perhaps it is the DeusEx executable itself that cannot handle the large value.
Update: hacking GetDiskFreeSpaceEx (and GetDiskFreeSpace) to limit the magnitude of the values returned doesn't seem to help. DeusEx must be using some other mechanism to get the free disk space.