https://bugs.winehq.org/show_bug.cgi?id=49920
--- Comment #7 from Alexandre Julliard julliard@winehq.org --- It's hard to tell without seeing all the details of your setup, but a valid WINEDLLPATH should work the same way before and after the change. Note that you can put multiple directories in WINEDLLPATH, for instance both 32-bit and 64-bit lib dirs.