http://bugs.winehq.org/show_bug.cgi?id=31943
--- Comment #6 from Rico kgbricola@web.de 2012-10-13 03:50:40 CDT --- No.
Build the latest libxcb from git without any additional patches (should be version 1.9 and use it, see http://forum.winehq.org/viewtopic.php?f=2&t=17203 - but skip the parts "wget ..." and "git apply ...") OR try "Add the X11/GL lock back around XCheckIfEvent". The libxcb version test is preferred. If it fixes the issue, then it's a dupe.
There is no statement about if it is a regression... If it is and the libxcb test doesn't solve it, please run a regression test http://wiki.winehq.org/RegressionTesting .
Wine should not be able to lock down your computer. You may try to switch to a terminal and back (strg + alt + fX) and/or run the game for testing proposes in wines virtual desktop.