http://bugs.winehq.org/show_bug.cgi?id=28898
--- Comment #76 from Joshua wine@placesthroughtime.com 2012-04-21 01:07:23 CDT --- (In reply to comment #75)
As an independent confirmation, I could not get the game to load until: Applying Erich solution from: http://source.winehq.org/patches/data/85573 into the latest wine-git source this was built on amd64, on Ubuntu latest 11.10 and patched wine-git. The full game setup from (today's) free Diablo III beta week-end trial installed and ran without a problem, it has now been running for hours and in network mode with a party doing quests. The only issue so far: could not change the graphics mode, the game quit, besides this the game looks platinum -- just needs this 1 fix. Thanks to this thread!
See if that graphics mode issue is the same as the one in bug 28201, theres a patch there as well.