http://bugs.winehq.org/show_bug.cgi?id=12165
--- Comment #6 from Vladimir vladimiroski@gmail.com 2008-03-27 07:13:07 --- No, it does not happend on my system.
But I'm not sure about the toolbar thing is a bug on Wine, as there was a recently fixed bug on ePlus about Toolbar icons widths, but it was affecting only when ePlus (eMule Plus) was set to Russian and other similar languages, anyway I had been using ePlus on wine since 2007 and never saw that problem of the toolbars.
For the height of the items on the preferences dialog I'm not very sure why exactly it behave different on your system, sometimes I start the program and got ePlus the same way as your screenshot, other times much worse and sometimes is much better (as in my first screenshoot).
I'll post a screenshot the next time I restart ePlus, just to see if it's persistent on the height of the items.