http://bugs.winehq.org/show_bug.cgi?id=25015
--- Comment #1 from Dan Kegel dank@kegel.com 2010-11-03 04:54:15 CDT --- I killed and restarted it, and it happily continued; right from the start, it used 96 pipes (all in one process!), 75 to 93 established tcp sessions (varying rapidly), 57 UDP sockets (connected to lots of different peers, plus three nonconnected), and 116 other fds, mostly local files.
So it was definitely happier after restart.