http://bugs.winehq.org/show_bug.cgi?id=18728
--- Comment #33 from Roderick Colenbrander thunderbird2k@gmail.com 2010-07-05 14:30:40 --- The issue is only similar if you disable multisampling in my test and force multisampling in nvidia-settings else only the error is similar but in the drivers the code path is likely the same.
After the fixes the Nvidia guy is implementing, the Nvidia drivers will still be buggy in some cases. He said he won't handle cases like the ones you point to like blitting between a multisampled fbo (lets say at 4x) and a system framebuffer (lets say at 2x) in case you will still get a GL_INVALID_OPERATION error. Also the nvidia-settings override are not hidden to the application anyway. If you would query GL_SAMPLES_ARB it would show 16x if you select that.