http://bugs.winehq.org/show_bug.cgi?id=58267
--- Comment #1 from ToastyBug cemer99797@isorax.com --- If launched with the D3D12 renderer instead of the default OpenGL renderer, this is the error from the BigPEmu log:
Error: Failed to create a graphics device context. This indicates a driver problem. Error: Video init failure: BigPEmu_Video_D3D12
To use the D3D12 renderer, launch with: wine ~/BigPEmu/BigPEmu.exe * -logging -setcfgprop VideoPlugin BigPEmu_Video_D3D12