https://bugs.winehq.org/show_bug.cgi?id=44395
--- Comment #44 from noabody@yahoo.com --- This appears to be a bug in the closed-source Nvidia proprietary driver. wine-preloader relies on published information to setup the pre-environment for code execution. Somehow Nvidia's code is non-conformant.
It's important to note that this bug "hides" itself in the maintainer version of Debian based Linux distros because wine-preloader is an optional component that is not normally installed. This is not the case with winehq.
My work-around was designed to be an "elegant" solution. Package management is unaffected by disabling wine-preloader through removal of its executable bit:
sudo chmod -x /opt/wine-devel/bin/wine-preloader or sudo chmod -x /opt/wine-stable/bin/wine-preloader