http://bugs.winehq.org/show_bug.cgi?id=12962
--- Comment #4 from Vitaliy Margolen vitaliy@kievinfo.com 2008-05-12 08:57:49 --- This means it's acompiz bug and not Wine's. You should probably file bug there. If it messing with mouse & keyboard input in anyway it will for sure break Wine. The input is really picky about lots of things.