https://bugs.winehq.org/show_bug.cgi?id=48584
--- Comment #2 from Scott shagooserver@gmail.com --- The bug is in part as you described, that DXVK is effecting an unrelated prefix.
To give a bit more detail the DTS-MA window pops up correctly for about 1 second then just turns completely black. It seems that when the DTS-MA program connects to it's client there is a change in the buffer size from 600 x 343 to 864 x 701 which may be the cause of the problem.
I do not understand what you want when you ask for the value of the wine prefix.
I use a desktop launcher to start DTS-MA as follows:
[Desktop Entry] Exec=konsole --workdir /home/scott/.winedts/drive_c/"Program Files"/DTS/MAS-SAS -e bash -c "WINEPREFIX=~/.winedts wine cmd | wine dtshd.exe" Icon=/home/scott/Pictures/icons/dts.ico Name=DTS MA StartupNotify=true Terminal=false Type=Application X-KDE-SubstituteUID=false
Although running the program from the installed directory gives the same result.
I do not have sufficient knowledge to determine whether the bug is in DXVK or not, or whether there are 2 bugs, one in wine and one in DXVK. If you are able to clarify this for me I am more than happy to take up the issue with them.