http://bugs.winehq.org/show_bug.cgi?id=18285
--- Comment #8 from Jesse Allen the3dfxdude@gmail.com 2009-09-13 11:43:24 --- I just confirmed the actual game also will receive input from the desktop outside of the game window. i.e. the mouse cursor in game will move if you have the virtual desktop showing and you move the mouse on the outside of the wine.