http://bugs.winehq.org/show_bug.cgi?id=58115
--- Comment #13 from J.V. jveikanm@nic.fi --- (In reply to Zeb Figura from comment #12)
Is this meant to access a device actively in use by the host? That's unlikely to be possible.
Yes. And it's pretty absurd that I could update the firmware with VirtualBox a few years ago. They dropped NVMe support. And VMware was sold to Broadcom.