https://bugs.winehq.org/show_bug.cgi?id=44250
--- Comment #4 from andrew@alshain.org.uk --- I managed to copy my savedgames to a laptop with a AMD A6 processor (mullin GPU), also using the amdgpu driver and this crash doesn't occur. It's running a slightly out-of-date antergos distribution based on Arch:
kernel: 4.13.8-1-ARCH mesa: 17.2.3-1 wine: 2.19.1
I can save the game on the level that causes the crash, copy that savedgame back to the machine producing the crash, and loading the savedgame instantly crashes with the same error and suspicious register value. Loading the same savedgame on the laptop works fine.
This is not the only part of game that results in a repeatable crash. Two other locations that spring to mind that on entering result in the same crash are the hunting lodge on Tatooine, and on leaving the airlock to walk outside to get to the bridge on the Leviathan. Loading those savedgames on the laptop works with no problems.
It is possible to continue playing after that level on the machine that experiences the crash, but as mentioned there are other instances of that (presumably the same) bug occuring on later levels.