https://bugs.winehq.org/show_bug.cgi?id=39053
--- Comment #10 from super_man@post.com ---
Also if the issue appears I'm hearing disk activity in an interval of 1 second. Maybe this issue has something to do with I/O.
An old hdd, slow/breaking apart, bad cable? I am unable to hear any disk activity with recent hard disks. They are just too silent. It's a bit odd problem if you dont see it at every start. If you could you should try another hard disk if that makes any difference.