http://bugs.winehq.org/show_bug.cgi?id=10509
--- Comment #13 from Jani-Matti Hätinen jani-matti.hatinen@iki.fi 2008-01-14 10:01:39 --- I get the same backtrace as above when trying to run System Shock 2 after applying all unofficial patches and fixes with SS2Tool (currently available from http://www.strangebedfellows.de/index.php?topic=392.0).
SS2Tool is the recommended way to make System Shock 2 run on native Windows 2000 & XP systems (without patching the game won't work on native systems either).
Again the game works fine with an emulated desktop, apart from not blanking the mouse cursor.