https://bugs.winehq.org/show_bug.cgi?id=47128
--- Comment #9 from Luca lukycrociato@gmail.com --- I have an update on this, it's not wine-related.
I reproduced the same environment using DXVK on Windows, and it lags the same, probably related to some sort of shader compile.
So it's related to the game engine which behaves bad with Vulkan, I have to say it's the only game I know doing this