https://bugs.winehq.org/show_bug.cgi?id=43750
--- Comment #5 from Alex Henrie alexhenrie24@gmail.com --- Furthermore, because you reported this, starting in Wine 2.21 ttyACM devices will be mapped to COM ports automatically. In your case, /dev/ttyACM0 will be COM5 by default. And you're welcome :-)
https://source.winehq.org/git/wine.git/commitdiff/4177068d5a1f30f0ad14f67368...