http://bugs.winehq.org/show_bug.cgi?id=25727
--- Comment #4 from Will Temple willmtemple@gmail.com 2011-02-13 10:56:47 CST --- Note, I've found that if I launch the game, and then switch to a different desktop where no windows are present before the game launches, the game will launch on that desktop in full screen at 1680x1050@155H.
Other note: Wine Forum user "vitamin" gave me this command for launching:
(Should be run from "steamapps/common/dead space 2")
"wine explorer /desktop=deadspace2,1680x1050 deadspace2.exe"
(Replace 1680x1050 with your resolution.)
The command will launch dead space 2 in a separate Virtual Desktop, without requiring Steam to be in VD.