https://bugs.winehq.org/show_bug.cgi?id=38668
--- Comment #56 from Kimmo Myllyvirta kimmo.myllyvirta@gmail.com --- Thanks, I guessed it won't be that easy to fix it. I'll try to figure out some better patch that works for everyone/thing (that one breaks some tests etc).
I bought the game and it does fail similarly with a clean prefix. (I played it up to chapter 5 with the hack patch with not-so-clean prefix at first, no crashes). Skyrim SE is much easier to test, since the native xaudio2_7 crashes there almost immediately after launching it.
There are two possible approaches for fixing this (if it is even worth fixing - the bug is in native xaudio2_7, use builtin instead), either try to adjust the memory layout, or prefer/enforce bottom-up allocations. But really, both of these would be just hacks.