http://bugs.winehq.org/show_bug.cgi?id=33886
--- Comment #11 from bart@wina.ugent.be 2013-06-26 05:34:59 CDT --- my idea is (but this is just an idea) that there's something wrong with the path file handling: -> when running autostart.exe, the program loads itself from cd-rom image, loads a basic amount of code from cd-rom image for the program start (the cdrom has a 1602.exe on-board, and keeps running until we reach the point where it actually needs to prepare itself for a real "run", eg: no more running from cdrom (loading files ...) -> when invoking the program directly, it tries to load everything locally, fails horribly, and generates a pf error due to missing dlls / ...
this might fit, but I'm not a wine expert