http://bugs.winehq.org/show_bug.cgi?id=18614
--- Comment #13 from Ken Sharp kennybobs@o2.co.uk 2011-04-19 19:48:36 CDT --- And you completely cleaned ~/.wine ?
If not, try "rm -rf ~/.wine" and try again.
If you still have a problem, although I don't know how useful it will be, try WINEDEBUG=+relay,+seh,+tid winecfg &> winecfg.log
winecfg.log won't be small so you will need to compress it with decent compression and attach it here.
Also, what file system are you using?