https://bugs.winehq.org/show_bug.cgi?id=55899
--- Comment #3 from Gabriel Ivăncescu gabrielopcode@gmail.com --- Ah yeah, probably because it gets added to x86_64 as well, which obviously doesn't support 4-byte stack alignment. You'll have to add it only to the i386_CFLAGS (not sure if that's possible with env vars, but you can just edit the Makefile manually after it's generated and add them).