https://bugs.winehq.org/show_bug.cgi?id=42675
--- Comment #31 from Mr.Midnight camdenorrb@me.com --- I just "solved" the issue by subtracting 10 from the height and 5 from the width in the virtual desktop, I then forced it to "fullscreen" with `wmctrl -r nameofwindow -b add,fullscreen` this results in a window with parts of the right and bottom cut out but allows you to play normally with close to the full resolution. Unfortuantly I don't have much knowledge of the backend of wine, but I'm guessing Overwatch is requesting a smaller resolution as there are normally black lines on the top and bottom of the game window and wine isn't listening to this request which makes it misplace the mouse on the screen making a movement upwards.