https://bugs.winehq.org/show_bug.cgi?id=49752
--- Comment #1 from amad4wine2020@gmail.com --- On Windows 10 system I get 'Device not responding' (when nothing is actually connected to the serial port). On WINE (Ubuntu 20.04) I get 'Selected serial port not exist'.
Tested under VirtualBox with virtual COM port. ttyS1 - VirtualBox serial port (Port Mode: Disconnected)
The permissions seems correct to me. My user is added to the corresponding group.
auser@auser-VirtualBox:~$ ls -la /dev/ttyS1 crw-rw---- 1 root dialout 4, 65 Sep 4 02:46 /dev/ttyS1
auser@auser-VirtualBox:~$ cat /etc/group | grep dial dialout:x:20:auser