http://bugs.winehq.org/show_bug.cgi?id=16761
--- Comment #4 from M.Kiesel winehq.org@continuity.cjb.net 2009-02-19 11:12:47 --- I do understand that SC currently needs 48kHz default sample rate in Wine. This is not a "how do I get this working in Wine" bug but a "this is supposed to work but doesn't" bug :-). Clearly SC should work with 44kHz sample rate, too. As explained in comment 2 I suspect something's broken in Wine.
The fact that FA works with 44kHz *only* might be the same problem: Seems FA does mixing with 44kHz and Wine fails to resample to 48kHz.
Should check the sound data stream coming from the game; I very much doubt it's silent for the "mismatched" case.