https://bugs.winehq.org/show_bug.cgi?id=49170
--- Comment #16 from blc blc+wine@mail.vanade.com --- I'm a bit hesitant to post this as it may warrant its own bug report, but after I finally got WoW to work again on another machine, it likewise seems to have similar issues.
I also see this psychedelic coloring on my Intel HD graphics as well but only in DX11 Legacy renderer. Switching to DX11 mainline, with its associated FPS loss, does not seem to exhibit this. One easy to locate feature in the game that seems to exhibit this issue is looking at the Stormwind water fountain between the bank and the auction house - the water will look brightly colored with hints of glyphs when the issue manifests.
Oddly enough, despite having Windows 7 on this machine, I cannot run WoW in Windows anymore - it hangs on startup, so I can't compare with Windows.