https://bugs.winehq.org/show_bug.cgi?id=40121
--- Comment #5 from Mikko Tuumanen winebugzilla@k2c42.dy.fi --- No, I haven't solved this. This is only a guess, but perhaps NovaLCT mars gets a list of com ports like the MiniComPort.exe does and when the list is erroneously empty it just reports no com ports to the user.
I think the problem with MiniComPort.exe should be fixed first and if that doesn't help then do something else to fix NovaLCT-Mars.
And no, I haven't tried this on OS X.