http://bugs.winehq.org/show_bug.cgi?id=27298
--- Comment #28 from TestSubject sirbubbles01@gmail.com 2012-11-12 13:36:09 CST --- (In reply to comment #26)
Already disabled GLSL and the CPU and GPU are also OCed. As for the CPU itself it's more than adequate for this particular game. Honestly I've already done all of the "obvious" things. This bug wasn't posted because I'm looking for those sorts of "solutions", I'm looking for where Wine itself is getting hung up because I've narrowed down basically everything else.
Thanks for trying though.
You may find that either creating a new wine prefix, or removing any dll overrides such as any of the d3dx9 overrides, will make a massive difference to performance. I just stumbled upon this a couple of days ago, and have even been able to increase the quality of my settings slightly with far better performance than I have ever had in this game. Give it a try.