https://bugs.winehq.org/show_bug.cgi?id=56002
--- Comment #8 from Shmerl shtetldik@gmail.com --- So far the working combination for me was like this (still stuck with Plasma 5 but Plasma 6 is coming to Debian soon so I'll retest):
Run the game in Wine-Wayland mode (no XWayland) Enable in-game vsync setting
With XWayaland it's worse, no matter what setting this bug pops up.