https://bugs.winehq.org/show_bug.cgi?id=45623
--- Comment #28 from Markus Linnala markus.linnala+winehq@gmail.com --- Focusrite Scarlett sometimes gets out of sync and is in error state. Usually it happens when program starts and it initializes audio. You can hear it, like snap snap snap. If there is out of sync situation, then the device shows error lights (two input level lights are red) and to fix it I usually disconnect devices USB and reconnect. And after the device is up again everything works as expected. This can happen for example when SC2 starts, during loading screen before there is any real sounds.
It probably was this what you are looking, sorry I can't remember exactly and this is kind of automatic and I forgot. I'll still give a try in couple of days.
Thank you,